Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A streamlined method for transposon mutagenesis of Rickettsia parkeri yields numerous mutations that impact infection.

PloS one - 1 Jan 2018

Lamason Rebecca L, Kafai Natasha M, Welch Matthew D

Abstract excerpt

The rickettsiae are obligate intracellular alphaproteobacteria that exhibit a complex infectious life cycle in both arthropod and mammalian hosts. As obligate intracellular bacteria, rickettsiae are highly adapted to living inside a variety of host cells, including vascular endothelial cells during mammalian infection. Although it is assumed that the rickettsiae produce numerous virulence factors that usurp or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorocebus aethiops
Share to DNA Transposable Elements
Share to Genes, Reporter

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Green Fluorescent Proteins

Share to Rickettsia

Share to Transposases

Share to Vero Cells

Share to Virulence Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 29723287
DOI: 10.1371/journal.pone.0197012
PMCID: PMC5933787

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A streamlined method for transposon mutagenesis of Rickettsia parkeri yields numerous mutations that impact infection.PMID 29723287Read ↗

Transposon mutagenesis as an approach to improved understanding of Borrelia pathogenesis and biologySemantic proximity Read ↗

An expanded genetic toolkit for inducible expression and targeted gene silencing in <i>Rickettsia parkeri</i>Semantic proximity Read ↗

A patatin-like phospholipase mediates <i>Rickettsia parkeri</i> escape from host membranesSemantic proximity Read ↗

The Rickettsial Ankyrin Repeat Protein 2 Is a Type IV Secreted Effector That Associates with the Endoplasmic ReticulumSemantic proximity Read ↗

Genome-wide transposon mutagenesis of Borrelia burgdorferi for identification of phenotypic mutants.Semantic proximity Read ↗

Multiple Ehrlichia chaffeensis Genes Critical for Its Persistent Infection in a Vertebrate Host Are Identified by Random Mutagenesis Coupled with In Vivo Infection Assessment.Semantic proximity Read ↗

A Rickettsia Genome Overrun by Mobile Genetic Elements Provides Insight into the Acquisition of Genes Characteristic of an Obligate Intracellular LifestyleSemantic proximity Read ↗

Evolution and diversity of Rickettsia bacteria.Semantic proximity Read ↗

Genomic evolution and adaptation of arthropod-associated RickettsiaSemantic proximity Read ↗

Metagenome diversity illuminates origins of pathogen effectorsSemantic proximity Read ↗

Analysis of an ordered, comprehensive STM mutant library in infectious Borrelia burgdorferi: insights into the genes required for mouse infectivity.Semantic proximity Read ↗

A metabolic dependency for host isoprenoids in the obligate intracellular pathogen <i>Rickettsia parkeri</i> underlies a sensitivity for the statin class of host-targeted therapeuticsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.