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Article

The Rickettsial Ankyrin Repeat Protein 2 Is a Type IV Secreted Effector That Associates with the Endoplasmic Reticulum

25 Jun 2018

Abstract excerpt

ABSTRACT Strains of Rickettsia rickettsii , the tick-borne agent of Rocky Mountain spotted fever, vary considerably in virulence. Genomic comparisons of R. rickettsii strains have identified a relatively small number of genes divergent in an avirulent strain. Among these is one annotated asRickettsiaankyrin repeat protein 2 (RARP-2). Homologs of RARP-2 are present in all strains of R. rickettsii , but the protein...

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PMID: 29946049
DOI: 10.1128/mbio.00975-18

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