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Article

A protective protein antigen of Rickettsia rickettsii has tandemly repeated, near-identical sequences

1 Sept 1990

Abstract excerpt

The nucleotide sequence of a Rickettsia rickettsii gene that encodes a high-molecular-mass surface antigen (190 kilodaltons), which elicits protective immunity, was determined. The 6,747-nucleotide gene coded for a 2,249-amino-acid protein with a calculated molecular weight of 224,321. A 3.8-kilobase PstI fragment proximal to the 5' end of the gene was found to consist of 13 highly related tandem repeats which...

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PMID: 2117568
DOI: 10.1128/iai.58.9.2760-2769.1990

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