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Article

Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development.

Developmental biology - 15 Apr 2011

Tateya Tomoko, Imayoshi Itaru, Tateya Ichiro, Ito Juichi, Kageyama Ryoichiro

Abstract excerpt

Notch-mediated lateral inhibition has been reported to regulate auditory hair cell and supporting cell development from common precursors. While the Notch effector genes Hes1, Hes5 and Hey1 are expressed in the developing cochlea, inactivation of either of them causes only mild abnormality, suggesting their functional redundancy. To explore the roles of Hes/Hey genes in cochlear development, we examined compound...

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Identifiers

PMID: 21300049
DOI: 10.1016/j.ydbio.2011.01.038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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