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Article

Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea.

PloS one - 1 Jan 2013

Korrapati Soumya, Roux Isabelle, Glowatzki Elisabeth, Doetzlhofer Angelika

Abstract excerpt

In mammals, auditory hair cells are generated only during embryonic development and loss or damage to hair cells is permanent. However, in non-mammalian vertebrate species, such as birds, neighboring glia-like supporting cells regenerate auditory hair cells by both mitotic and non-mitotic mechanisms. Based on work in intact cochlear tissue, it is thought that Notch signaling might restrict supporting cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24023676
DOI: 10.1371/journal.pone.0073276
PMCID: PMC3758270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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