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Article

Investigation of CTLA-4 and CD28 gene polymorphisms in patients with diabetes mellitus type 2 using PCR-RFLP in a Turkish population.

The West Indian medical journal - 1 Jun 2010

Uzer E, Dilmec F, Akkafa F, Boduroglu O, van Kuilenburg A B P

Abstract excerpt

OBJECTIVE: The aim of this study is to investigate whether specific polymorphisms in the CTLA-4 and CD28 gene are associated with Type 2 diabetes mellitus (T2DM). METHODS: Blood samples were collected from 241 individuals (72 patients with T2DM and 169 healthy individuals) and DNA was isolated. A polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method was used to detect the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21291098

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