Article
Association of interleukin-4 promoter polymorphisms in Taiwanese patients with type 2 diabetes mellitus.
Metabolism: clinical and experimental - 1 Dec 2010
Ho Kuo-Ting, Shiau Ming-Yuh, Chang Yih-Hsin, Chen Chuan-Mu, Yang Shun-Chun, Huang Chien-Ning
Abstract excerpt
Many factors have been implicated in the onset of type 2 diabetes mellitus (T2DM). Recently, immune response and inflammation were suggested to play certain roles in the development and complications of T2DM. The aim of this study is to investigate the putative correlation between the promoter polymorphisms of interleukin-4 (IL-4), one of the immune-regulatory type 2 helper T-cell cytokines, and T2DM. Genomic DNA...
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