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Article

Association of CTLA-4 gene 49A/G polymorphism with the incidence of type 1 diabetes mellitus in the Iranian Kurdish population.

Pakistan journal of biological sciences : PJBS - 15 Dec 2013

Ahmadi Slahadin, Rostamzadeh Jalal, Khosravi Darya, Shariati Parvin, Shakiba Nadia

Abstract excerpt

Cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) has an inhibitory function on T cells and is critical for the induction of peripheral tolerance. CTLA-4 +49 G allele affects the CTLA-4 function and has been reported to be correlated with a higher risk of various autoimmune diseases including type 1 diabetes (T1D). The present study was conducted to investigate the association between the polymorphism of the...

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Identifiers

PMID: 24517008
DOI: 10.3923/pjbs.2013.1929.1935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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