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Article

Association of single nucleotide polymorphisms in cytotoxic T-lymphocyte antigen 4 and susceptibility to autoimmune type 1 diabetes in Tunisians.

Clinical and vaccine immunology : CVI - 1 Sept 2010

Benmansour Jihen, Stayoussef Mouna, Al-Jenaidi Fayza A, Rajab Mansoor H, Rayana Chiheb B, Said Hichem B, Mahjoub Touhami, Almawi Wassim Y

Abstract excerpt

In addition to HLA and insulin genes, the costimulatory molecule CTLA-4 gene is a confirmed type 1 diabetes (T1D) susceptibility gene. Previous studies investigated the association of CTLA-4 genetic variants with the risk of T1D, but with inconclusive findings. Here, we tested the contributions of common CTLA-4 gene variants to T1D susceptibility in Tunisian patients and control subjects. The study subjects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20610662
DOI: 10.1128/CVI.00099-10
PMCID: PMC2944459

Genes

GCG
MAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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