Association of miR-499, miR-27a, and miR-34a Gene Polymorphisms With Susceptibility to Type 2 Diabetes Mellitus in an Iranian Population: A Case-Control Study.

doi:10.1155/bmri/8927160

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Article

Association of miR-499, miR-27a, and miR-34a Gene Polymorphisms With Susceptibility to Type 2 Diabetes Mellitus in an Iranian Population: A Case-Control Study.

BioMed research international - 1 Jan 2026

Behdani Mehrdad, Hashemi Mohammad, Kaykhaei Mahmoud Ali, Bahari Masoumeh, Taheri Mohsen, Bahari Gholamreza

Abstract excerpt

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a multifactorial metabolic disorder influenced by both environmental and genetic factors. MicroRNAs (miRNAs) are involved in the regulation of insulin signaling, inflammation, and pancreatic β-cell function. Genetic polymorphisms in miRNA-related regions may contribute to interindividual differences in T2DM susceptibility, although their functional effects remain...

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Topics

Humans
MicroRNAs
Diabetes Mellitus, Type 2
Iran
Case-Control Studies
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Polymorphism, Single Nucleotide

Middle Aged

Male

Genetic Association Studies

Gene Frequency

Genotype

Source

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Identifiers

PMID: 42713823
DOI: 10.1155/bmri/8927160
PMCID: PMC13555612

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