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Article

Association of cytotoxic T-lymphocyte associated antigen 4 gene polymorphism with type 1 diabetes mellitus: a meta-analysis.

Gene - 25 Oct 2012

Tang Song-tao, Tang Hai-qin, Zhang Qiu, Wang Chang-jiang, Wang You-min, Peng Wen-jia

Abstract excerpt

To evaluate the association between costimulatory molecule cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) gene polymorphism and type 1 diabetes mellitus(T1DM), sixty-three published studies before December, 2011 were included. Meta-analysis was performed for each genotype in a random/fixed effect model. The combined odds ratio (OR) with 95% confidence interval (95%CI) was calculated to estimate the strength...

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Identifiers

PMID: 22964358
DOI: 10.1016/j.gene.2012.07.044

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