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Article

Analysis of CD28 and CTLA-4 gene polymorphisms in Turkish patients with Behcet's disease.

International journal of immunogenetics - 1 Feb 2007

Gunesacar R, Erken E, Bozkurt B, Ozer H T, Dinkci S, Erken E G, Ozbalkan Z

Abstract excerpt

In this study we aimed to investigate IVS3 +17T/C single nucleotide polymorphism (SNP) of CD28 gene, +49A/G and -318C/T SNPs of CTLA-4 gene in patients with Behçet's disease (BD) and their potential association to the main clinical features of the disease. These polymorphisms were investigated in a Turkish population of 123 patients with BD and 179 healthy controls, by using PCR-RFLP technique. HLA-B*51 genotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17284227
DOI: 10.1111/j.1744-313X.2007.00655.x

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