Article
Association of CTLA-4 (+49A/G) gene Polymorphism with type 1 diabetes mellitus in Iraqi children.
Cellular and molecular biology (Noisy-le-Grand, France) - 31 May 2022
Al-Isawi Hasanain Riyadh, Safi Faiza, Muhammed Hayder A
Abstract excerpt
CTLA4 is a regulator gene for T cells and relates to autoimmune diseases. By using a case-control method, CTLA4 functional single-nucleotide polymorphisms for potential associations with Type 1 diabetes mellitus in an Iraqi children's population. ARMS-PCR method is used for genotyping +49AG (rs231775) variations in 60 obese children and 60 ethnically matched controls; all measured subjects were (fasting glucose,...
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