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Article

Bi-allelic gene targeting in mouse embryonic stem cells.

Methods (San Diego, Calif.) - 1 Apr 2011

Tate Peri H, Skarnes William C

Abstract excerpt

The EUCOMM and KOMP programs have generated targeted conditional alleles in mouse embryonic stem cells for nearly 10,000 genes. The availability of these stem cell resources will greatly accelerate the functional analysis of genes in mice and in cultured cells. We present a method for conditional ablation of genes in ES cells using vectors and targeted clones from the EUCOMM and KOMP conditional resources....

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Identifiers

PMID: 21288739
DOI: 10.1016/j.ymeth.2010.12.025
PMCID: PMC3572411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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