Article
Mammalian genome targeting using site-specific recombinases.
Frontiers in bioscience : a journal and virtual library - 1 Jan 2006
García-Otín Angel Luis, Guillou Florian
Abstract excerpt
Nowadays, a wide array of procedures in mouse technology has been made available to researchers in order to establish valuable models for the study of gene function. The efficiency of gene transfer and gene targeting as methods for producing genetic changes in mice, in addition to continuous advances in molecular biology tools, has converted the mouse into the major experimental model for the study of mammalian...
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