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Article

Generation of knockout alleles by RFLP based BAC targeting of polymorphic embryonic stem cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015

Barakat Tahsin Stefan, Gribnau Joost

Abstract excerpt

The isolation of germ line competent mouse Embryonic Stem (ES) cells and the ability to modify the genome by homologous recombination has revolutionized life science research. Since its initial discovery, several approaches have been introduced to increase the efficiency of homologous recombinati...

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Identifiers

PMID: 25239745
DOI: 10.1007/978-1-4939-1652-8_7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25239745-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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