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Article

Gene targeting in the mouse.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Griep Anne E, John Manorama C, Ikeda Sakae, Ikeda Akihiro

Abstract excerpt

Establishment of methods to inactivate genes by homologous recombination in embryonic stem (ES) cells has provided great advantages to the field of mouse genetics. Using this technology, a number of null mutant mice, so-called knock-out mice, have been generated. The gene-targeting technology offers a strong tool that allows us to understand the function of a particular gene of interest in the whole animal and...

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Identifiers

PMID: 21805269
DOI: 10.1007/978-1-61779-210-6_11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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