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Article

Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study.

Cancer causes & control : CCC - 1 Apr 2011

Levine A Joan, Lee Won, Figueiredo Jane C, Conti David V, Vandenberg David J, Davis Brian D, Edlund Christopher K, Henning Susanne M, Heber David, Stern Mariana C, Haile Robert W

Abstract excerpt

BACKGROUND: Folate-associated one-carbon metabolism (FOCM) is an important pathway in colorectal neoplasia risk but data on genetic variation in this pathway are largely limited to studies of single SNPs in selected genes. METHODS: We used a comprehensive tagSNP approach to study the association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21274745
DOI: 10.1007/s10552-011-9726-7
PMCID: PMC3059778

Genes

MTHFR
RFC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21274745-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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