Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genes involved with folate uptake and distribution and their association with colorectal cancer risk.

Cancer causes & control : CCC - 1 Apr 2010

Figueiredo Jane C, Levine A Joan, Lee Won H, Conti David V, Poynter Jenny N, Campbell Peter T, Duggan David, Lewinger Juan Pablo, Martinez Maria Elena, Ulrich Cornelia M, Newcomb Polly, Potter John, Limburg Paul J, Hopper John, Jenkins Mark A, Le Marchand Loic, Baron John A, Haile Robert W

Abstract excerpt

Folate status is an important predictor of colorectal cancer risk. Common genetic variants in genes involved in regulating cellular folate levels might also predict risk, but there are limited data on this issue. We conducted a family-based case-control association study of variants in four genes involved in folate uptake and distribution: FOLR1, FPGS, GGH and SLC19A1, using 1,750 population-based and 245...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Family Health
Share to Folic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Transport Proteins

Share to Peptide Synthases

Share to Receptors, Cell Surface

Share to Reduced Folate Carrier Protein

Share to Registries

Share to Surveys and Questionnaires

Source

Open in PubMed Open full text

Identifiers

PMID: 20037791
DOI: 10.1007/s10552-009-9489-6
PMCID: PMC2904058

Genes

FOLR1
FPGS
GGH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genes involved with folate uptake and distribution and their association with colorectal cancer risk.PMID 20037791Read ↗

Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study.Semantic proximity Read ↗

A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk.Semantic proximity Read ↗

Plasma folate, related genetic variants, and colorectal cancer risk in EPIC.Semantic proximity Read ↗

Folate intake and colorectal cancer risk according to genetic subtypes defined by targeted tumor sequencing.Semantic proximity Read ↗

How folate metabolism affects colorectal cancer development and treatment; a story of heterogeneity and pleiotropy.Semantic proximity Read ↗

Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry.Semantic proximity Read ↗

Folate-genetics and colorectal neoplasia: what we know and need to know next.Semantic proximity Read ↗

Polymorphisms of folate metabolism-related genes and survival of patients with colorectal cancer in the Korean populationSemantic proximity Read ↗

Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?Semantic proximity Read ↗

Folate-related polymorphisms in gastrointestinal stromal tumours: susceptibility and correlation with tumour characteristics and clinical outcome.Semantic proximity Read ↗

The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia.Semantic proximity Read ↗

Role of MTHFR polymorphisms and folate levels in different phenotypes of sporadic colorectal cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.