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Article

Genetic determinants of diabetes are similarly associated with other immune-mediated diseases.

Current opinion in allergy and clinical immunology - 1 Dec 2007

Duffy David L

Abstract excerpt

PURPOSE OF REVIEW: I discuss the increasing number of genes discovered to exert pleiotropic action on susceptibility to diabetes and simultaneously to other immune-mediated diseases. While a genetic correlation between type 1 diabetes and autoimmunity is not surprising, the mechanism of a relationship to other conditions such as atopy is less obvious. The recent wave of genome-wide association studies offers...

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Topics

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Share to Antigens, Differentiation
Share to CTLA-4 Antigen
Share to DEAD-box RNA Helicases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune System Diseases

Share to Interferon-Induced Helicase, IFIH1

Share to Interleukin-2 Receptor alpha Subunit

Share to PPAR gamma

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Source

Identifiers

PMID: 17989522
DOI: 10.1097/ACI.0b013e3282f1dc99

Genes

IFIH1
CTLA4
PPARG
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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