Article
Absence of preference for social novelty and increased grooming in integrin β3 knockout mice: initial studies and future directions.
Autism research : official journal of the International Society for Autism Research - 1 Feb 2011
Carter Michelle D, Shah Charisma R, Muller Christopher L, Crawley Jacqueline N, Carneiro Ana M D, Veenstra-VanderWeele Jeremy
Abstract excerpt
Elevated whole blood serotonin 5-HT, or hyperserotonemia, is a common biomarker in autism spectrum disorder (ASD). The integrin β3 receptor subunit gene (ITGB3) is a quantitative trait locus for whole blood 5-HT levels. Recent work shows that integrin β3 interacts with the serotonin transporter (...
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