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Article

Deficiency of a brain-specific chemokine-like molecule, SAM3, induces cardinal phenotypes of autism spectrum disorders in mice.

Scientific reports - 28 Nov 2017

Kim Sujin, Lee Boyoung, Choi Jung-Hwa, Kim Jong-Hyun, Kim Cheol-Hee, Shin Hee-Sup

Abstract excerpt

Chemokines are small secreted signaling proteins produced by a broad range of cells, including immune cells. Several studies have recently suggested potential roles of chemokines and their receptors in the pathophysiology of autism spectrum disorders (ASDs). SAM3 is a novel brain-specific chemokine-like molecule with an unknown physiological function. We explored the relevance of chemokines in the development of...

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Identifiers

PMID: 29184127
DOI: 10.1038/s41598-017-16769-5
PMCID: PMC5705707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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