Article
A mathematical model for progression and heterogeneity in colorectal cancer dynamics.
Theoretical population biology - 1 Jun 2011
Delitala Marcello, Lorenzi Tommaso
Abstract excerpt
This paper deals with the development of a mathematical model that describes cancer dynamics at the cellular scale. The selected case study concerns colon and rectum cancer, which originates in colorectal crypts. Cells inside the crypts are assumed to be organized according to a compartmental-like arrangement and to be homogeneously mixing. A mathematical model for cancer progression is proposed here. This model...
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