Article

Mathematical Modeling of Multiple Pathways in Colorectal Carcinogenesis using Dynamical Systems with Kronecker Structure

2020-08-14

Abstract excerpt

Like many other tumors, colorectal cancers develop through multiple pathways containing different driver mutations. This is also true for colorectal carcinogenesis in Lynch syndrome, the most common inherited colorectal cancer syndrome. However, a comprehensive understanding of Lynch syndrome tumor evolution which allows for tailored clinical treatment and even prevention is still lacking. We suggest a linear auto...

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Literature Corpus work: 404aa111-8b5c-5e5d-83eb-bcf43e7ff99d
DOI: 10.1101/2020.08.14.250175

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