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A Tissue Renewal-Based Mechanism Drives Colon Tumorigenesis

2025-11-19

Abstract excerpt

Our Goal is to identify how colorectal cancer (CRC) arises in the single-layered-cell epithelium (simple columnar epithelium) that lines the luminal surface of the large intestine. We recently reported that the dynamic organization of cells in colonic epithelium is encoded by five biological rules and conjectured that colon tumorigenesis involves an autocatalytic tissue renewal reaction. Our objective was to defin...

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Literature Corpus work
57f5385f-91c2-546d-aef2-2a07f4783e7f
DOI
10.20944/preprints202511.1397.v1
Open publication

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A Tissue Renewal-Based Mechanism Drives Colon TumorigenesisDOI 10.20944/preprints202511.1397.v1
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