CYP2D6 genotyping by liquid chromatography-electrospray ionization mass spectrometry.

doi:10.1007/s00216-010-4597-4

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Article

CYP2D6 genotyping by liquid chromatography-electrospray ionization mass spectrometry.

Analytical and bioanalytical chemistry - 1 Jun 2011

Beer Beate, Erb Robert, Pitterl Florian, Niederstätter Harald, Maroñas Olalla, Gesteira Alejandro, Carracedo Angel, Piatkov Irina, Oberacher Herbert

Abstract excerpt

Genetic polymorphisms can significantly affect the enzyme activity of the drug metabolizing enzyme Cytochrome P450 2D6 (CYP2D6; OMIM 124030). Accordingly, CYP2D6 genotyping is considered as a valid approach to predict the individual CYP2D6 metabolizing status. We introduce ion-pair reversed-phase high-performance liquid chromatography-electrospray ionization mass spectrometry (ICEMS) as method for the...

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PMID: 21225252
DOI: 10.1007/s00216-010-4597-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.