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CYP2D6 genotyping in a Korean cohort: comparative analysis with Asian, Caucasian, and African populations.

Pharmacogenomics - 1 Jan 2025

Kim Tak Don, Kwak Jung-Sook, Shin Jae-Gook, Kim Ho-Sook, Yoon Young-Ran, Gwon Mi-Ri, Kim Min-Gul, Moon Seol Ju, Lee SeungHwan, Park Chan Song, Song Ji Hye, Hong Jang Hee, Sunwoo Jung

Abstract excerpt

BACKGROUND: Cytochrome P450 2D6 (CYP2D6) is a highly polymorphic enzyme responsible for metabolizing approximately 20% of commonly prescribed drugs. Its genetic variability contributes to interindividual and interethnic differences in drug response. However, large-scale studies on CYP2D6 allele distributions in the Korean population remain limited. METHODS: We conducted CYP2D6 genotyping, including copy number...

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Black People
Cohort Studies
Cytochrome P-450 CYP2D6
DNA Copy Number Variations
East Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Republic of Korea

South Asian People

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Identifiers

PMID: 41003540
DOI: 10.1080/14622416.2025.2565993
PMCID: PMC12582055

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