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Article

MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms.

Clinical chemistry - 1 Jan 2007

Blievernicht Julia K, Schaeffeler Elke, Klein Kathrin, Eichelbaum Michel, Schwab Matthias, Zanger Ulrich M

Abstract excerpt

BACKGROUND: CYP2B6 is a highly variable and polymorphic cytochrome P450 (CYP) enzyme involved in the biotransformation of an increasing number of drugs, including cyclophosphamide, bupropion, and the nonnucleosidic reverse transcriptase inhibitor efavirenz. Several nonsynonymous and promoter sing...

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Source

Identifiers

PMID: 17082249
DOI: 10.1373/clinchem.2006.074856

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17082249-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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