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Article

The fitness cost of rifampicin resistance in Pseudomonas aeruginosa depends on demand for RNA polymerase.

Genetics - 1 Mar 2011

Hall Alex R, Iles James C, MacLean R Craig

Abstract excerpt

Bacterial resistance to antibiotics usually incurs a fitness cost in the absence of selecting drugs, and this cost of resistance plays a key role in the spread of antibiotic resistance in pathogen populations. Costs of resistance have been shown to vary with environmental conditions, but the causes of this variability remain obscure. In this article, we show that the average cost of rifampicin resistance in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 21220359
DOI: 10.1534/genetics.110.124628
PMCID: PMC3063675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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