Article
Environmental Dependence of Competitive Fitness in Rifampin-Resistant rpoB Mutants of Bacillus subtilis.
Applied and environmental microbiology - 8 Mar 2022
Leehan Joss D, Nicholson Wayne L
Abstract excerpt
RNA polymerase (RNAP) is a highly conserved macromolecular machine that contributes to the flow of genetic information from genotype to phenotype. In Bacillus subtilis, mutations in the rpoB gene encoding the β-subunit of RNAP have been shown to alter a number of global phenotypes, including grow...
Topics
- Anti-Bacterial Agents
- Bacillus subtilis
- Bacterial Proteins
- DNA-Directed RNA Polymerases
- Drug Resistance, Bacterial
- Mutation
- Rifampin