Article
Evolution of Escherichia coli rifampicin resistance in an antibiotic-free environment during thermal stress.
BMC evolutionary biology - 22 Feb 2013
Rodríguez-Verdugo Alejandra, Gaut Brandon S, Tenaillon Olivier
Abstract excerpt
BACKGROUND: Beneficial mutations play an essential role in bacterial adaptation, yet little is known about their fitness effects across genetic backgrounds and environments. One prominent example of bacterial adaptation is antibiotic resistance. Until recently, the paradigm has been that antibiotic resistance is selected by the presence of antibiotics because resistant mutations confer fitness costs in antibiotic...
Topics
- Adaptation, Physiological
- Amino Acid Substitution
- DNA-Directed RNA Polymerases
- Drug Resistance, Bacterial
- Escherichia coli
- Escherichia coli Proteins
- Evolution, Molecular
- Genetic Fitness
- Hot Temperature
- Microbial Sensitivity Tests