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Article

Reduction of the fitness cost of antibiotic resistance caused by chromosomal mutations under poor nutrient conditions.

Environment international - 1 Nov 2018

Lin Wenfang, Zeng Jie, Wan Kun, Lv Lu, Guo Lizheng, Li Xi, Yu Xin

Abstract excerpt

The prevalence of antibiotic resistance in drinking water system is pressing public health risk. Antibiotic resistance conferred by chromosomal mutations often produces fitness cost, which may affect its spread and persistence. In this study, the rifampin-resistant strains were competed with their wild-type counterparts at different nutrient levels. It was observed that the ratio of the absolute number between...

Topics

Bacteria
Chromosomes, Bacterial
Culture Media
Drug Resistance, Bacterial
Genetic Fitness
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30064056
DOI: 10.1016/j.envint.2018.07.035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-30064056-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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