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Article

The cost of multiple drug resistance in Pseudomonas aeruginosa.

Journal of evolutionary biology - 1 May 2009

Ward H, Perron G G, Maclean R C

Abstract excerpt

The spread of bacterial antibiotic resistance mutations is thought to be constrained by their pleiotropic fitness costs. Here we investigate the fitness costs of resistance in the context of the evolution of multiple drug resistance (MDR), by measuring the cost of acquiring streptomycin resistance mutations (StrepR) in independent strains of the bacterium Pseudomonas aeruginosa carrying different rifampicin...

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Identifiers

PMID: 19298493
DOI: 10.1111/j.1420-9101.2009.01712.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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