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Article

G(alpha)12/13 induction of CYR61 in association with arteriosclerotic intimal hyperplasia: effect of sphingosine-1-phosphate.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2011

Kim Young Mi, Lim Sung-Chul, Han Chang Yeob, Kay Hee Yeon, Cho Il Je, Ki Sung Hwan, Lee Moo Yeol, Kwon Hyuck Moon, Lee Chang Ho, Kim Sang Geon

Abstract excerpt

OBJECTIVE: Gα(12/13) play a role in oncogenic transformation and tumor growth. Cysteine-rich protein 61 (CYR61) is a growth-factor-inducible angiogenic factor. In view of potential overlapping functions between Gα(12/13) and CYR61, this study investigated the role of these G proteins in CYR61 induction in association with hyperplastic vascular abnormality. METHODS AND RESULTS: Overexpression of activated Gα(12)...

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PMID: 21212405
DOI: 10.1161/ATVBAHA.110.218552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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