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Article

Structural properties of MHC class II ligands, implications for the prediction of MHC class II epitopes.

PloS one - 30 Dec 2010

Jørgensen Kasper Winther, Buus Søren, Nielsen Morten

Abstract excerpt

Major Histocompatibility class II (MHC-II) molecules sample peptides from the extracellular space allowing the immune system to detect the presence of foreign microbes from this compartment. Prediction of MHC class II ligands is complicated by the open binding cleft of the MHC class II molecule, allowing binding of peptides extending out of the binding groove. Furthermore, only a few HLA-DR alleles have been...

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Identifiers

PMID: 21209859
DOI: 10.1371/journal.pone.0015877
PMCID: PMC3012731

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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