Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-peptide binding prediction using structural and modeling principles.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007

Kangueane Pandjassarame, Sakharkar Meena Kishore

Abstract excerpt

Short peptides binding to specific human leukocyte antigen (HLA) alleles elicit immune response. These candidate peptides have potential utility in peptide vaccine design and development. The binding of peptides to allele-specific HLA molecule is estimated using competitive binding assay and biochemical binding constants. Application of this method for proteome-wide screening in parasites, viruses, and virulent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computer Simulation
Share to HLA Antigens
Share to Immunogenetics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ligands

Share to Peptides

Share to Quantitative Structure-Activity Relationship

Share to Thermodynamics

Share to User-Computer Interface

Source

Identifiers

PMID: 18450009
DOI: 10.1007/978-1-60327-118-9_21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-peptide binding prediction using structural and modeling principles.PMID 18450009Read ↗

Class II HLA-peptide binding prediction using structural principles.Semantic proximity Read ↗

Toward more accurate pan-specific MHC-peptide binding prediction: a review of current methods and tools.Semantic proximity Read ↗

epitopepredict: A tool for integrated MHC binding predictionSemantic proximity Read ↗

Peptide binding motifs for MHC class I and II molecules.Semantic proximity Read ↗

TEPITOPEpan: extending TEPITOPE for peptide binding prediction covering over 700 HLA-DR molecules.Semantic proximity Read ↗

Homology modelling of frequent HLA class-II alleles: A perspective to improve prediction of HLA binding peptide and understand the HLA associated disease susceptibility.Semantic proximity Read ↗

Structural properties of MHC class II ligands, implications for the prediction of MHC class II epitopes.Semantic proximity Read ↗

Major histocompatibility complex linked databases and prediction tools for designing vaccines.Semantic proximity Read ↗

Evaluation of different generic in silico methods for predicting HLA class I binding peptide vaccine candidates using a reverse approach.Semantic proximity Read ↗

Novel<i>in silico</i>tools for designing peptide-based subunit vaccines and immunotherapeuticsSemantic proximity Read ↗

Predicted epitope binding core motifs and common amino acid polymorphisms distinguish protective- from susceptibility-associated HLA alleles in leishmaniasisSemantic proximity Read ↗

Performance Evaluation of MHC Class-I Binding Prediction Tools Based on an Experimentally Validated MHC–Peptide Binding Data SetSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.