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Article

An automated framework for understanding structural variations in the binding grooves of MHC class II molecules.

BMC bioinformatics - 18 Jan 2010

Yeturu Kalidas, Utriainen Tapani, Kemp Graham J L, Chandra Nagasuma

Abstract excerpt

BACKGROUND: MHC/HLA class II molecules are important components of the immune system and play a critical role in processes such as phagocytosis. Understanding peptide recognition properties of the hundreds of MHC class II alleles is essential to appreciate determinants of antigenicity and ultimately to predict epitopes. While there are several methods for epitope prediction, each differing in their success rates,...

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Identifiers

PMID: 20122230
DOI: 10.1186/1471-2105-11-S1-S55
PMCID: PMC3009528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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