Article
Analysis of the structure of naturally processed peptides bound by class I and class II major histocompatibility complex molecules.
EXS - 1 Jan 1995
Appella E, Padlan E A, Hunt D F
Abstract excerpt
Antigen-specific T-cell responses require antigenic peptides presented on the cell surface by the major histocompatibility complex (MHC) molecules. The structural characteristics of these peptides are being defined. It is now known that the majority of peptides that associate with MHC Class I are 8-10 residues long, with allotype-specific binding motifs containing up to three anchor positions. This is consistent...
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