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Article

Class II HLA-peptide binding prediction using structural principles.

Human immunology - 1 Mar 2009

Mohanapriya Arumugam, Lulu Sajitha, Kayathri Rajarathinam, Kangueane Pandjassarame

Abstract excerpt

The precise prediction of class II human leukocyte antigen (HLA) peptide binding finds application in epitope design for the development of vaccines and diagnostics of diseases associated with CD4+ T-cellular immunity. HLA II binding peptides have an extended conformation at the binding groove unlike class I. This increases peptide binding combinations of varying length at the groove, having an eventual effect in...

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Share to CD4-Positive T-Lymphocytes
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Share to Epitopes, T-Lymphocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19187794
DOI: 10.1016/j.humimm.2008.12.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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