Article

epitopepredict: A tool for integrated MHC binding prediction

2021-02-07

Abstract excerpt

A key step in the cellular adaptive immune response is the presentation of antigen to T cells. During this process short peptides processed from self or foreign proteins may be presented on the surface bound to MHC molecules for binding to T cell receptors. Those that bind and activate an immune response are called epitopes. Computational prediction of T cell epitopes has many applications in vaccine design and im...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3ae12241-e0f4-55dd-a0bf-a919acb3288e
DOI: 10.1101/2021.02.05.429892

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

epitopepredict: A tool for integrated MHC binding predictionDOI 10.1101/2021.02.05.429892Read

TepiTool: A Pipeline for Computational Prediction of T Cell Epitope Candidates.Semantic proximity Read

T Cell Epitope PredictionsSemantic proximity Read

Benchmarking predictions of MHC class I restricted T cell epitopes in a comprehensively studied model system.Semantic proximity Read

Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopesSemantic proximity Read

NetTepi: an integrated method for the prediction of T cell epitopesSemantic proximity Read

Major histocompatibility complex linked databases and prediction tools for designing vaccines.Semantic proximity Read

EpiDOCK: a molecular docking-based tool for MHC class II binding prediction.Semantic proximity Read

Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan.Semantic proximity Read

Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes.Semantic proximity Read

TEPITOPEpan: extending TEPITOPE for peptide binding prediction covering over 700 HLA-DR molecules.Semantic proximity Read

Class II HLA-peptide binding prediction using structural principles.Semantic proximity Read

Performance Evaluation of MHC Class-I Binding Prediction Tools Based on an Experimentally Validated MHC–Peptide Binding Data SetSemantic proximity Read