Article
TEPITOPEpan: extending TEPITOPE for peptide binding prediction covering over 700 HLA-DR molecules.
PloS one - 1 Jan 2012
Zhang Lianming, Chen Yiqing, Wong Hau-San, Zhou Shuigeng, Mamitsuka Hiroshi, Zhu Shanfeng
Abstract excerpt
MOTIVATION: Accurate identification of peptides binding to specific Major Histocompatibility Complex Class II (MHC-II) molecules is of great importance for elucidating the underlying mechanism of immune recognition, as well as for developing effective epitope-based vaccines and promising immunotherapies for many severe diseases. Due to extreme polymorphism of MHC-II alleles and the high cost of biochemical...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
