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Article

Haplotype effect in the IGF1 promoter accounts for the association between microsatellite and serum IGF1 concentration.

Clinical endocrinology - 1 Apr 2011

Chen Holly Y, Chan Iris H S, Sham Aprille L K, Leung Vincent H K, Ma Suk L, Ho Suzanne C, Tang Nelson L S

Abstract excerpt

OBJECTIVE: Systemic insulin-like growth factor 1 (IGF1) level is an important risk factor for various diseases. The inter-individual variation of serum IGF1 is determined by environmental and genetic factors, which are attributed to a microsatellite in IGF1 promoter. However, the exact nature of the underlying regulatory elements accounting for this association has not been characterized. Here, we defined the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21198739
DOI: 10.1111/j.1365-2265.2010.03962.x

Genes

IGF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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