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Article

Comprehensive evaluation of genetic variation in the IGF1 gene and risk of prostate cancer.

International journal of cancer - 1 Feb 2007

Johansson Mattias, McKay James D, Stattin Pär, Canzian Federico, Boillot Catherine, Wiklund Fredrik, Adami Hans-Olov, Bälter Katarina, Grönberg Henrik, Kaaks Rudolf

Abstract excerpt

Insulin-like growth factor-I (IGF1) stimulates cell proliferation, decreases apoptosis, and has been implicated in cancer development. Epidemiological studies have shown elevated levels of circulating IGF1 to be associated with increased risk of prostate cancer. To what extent genetic variation in the IGF1 gene is related to prostate cancer risk is largely unknown. We performed a comprehensive haplotype tagging...

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Identifiers

PMID: 17096324
DOI: 10.1002/ijc.22344

Genes

IGF1
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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