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Article

Association of IGF1 gene haplotypes with high myopia in Chinese adults.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Feb 2012

Mak Joey Y Y, Yap Maurice K H, Fung Wai Yan, Ng Po Wah, Yip Shea Ping

Abstract excerpt

OBJECTIVE: To investigate the association of high myopia with common single-nucleotide polymorphisms (SNPs) in the IGF1, IGFBP3, and IGFBP4 genes in a Chinese population. METHODS: For our case-control study, we recruited 600 unrelated participants: 300 case participants with high myopia (-8.00 diopters or less) and 300 emmetropic controls (within ±1.00 diopter). Twenty-one tag SNPs were selected from these...

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Source

Identifiers

PMID: 22332214
DOI: 10.1001/archophthalmol.2011.365

Genes

IGF1
IGFBP3
IGFBP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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