Article
Single-nucleotide polymorphisms and haplotype LD analysis of the 29-kb IGF2 region on chromosome 11p15.5 in the Korean population.
Human heredity - 1 Jan 2005
Lee Hye-Ja, Kim Kwang-Joong, Park Mi-Hyun, Kimm Kuchan, Park Chan, Oh Bermseok, Lee Jong-Young
Abstract excerpt
OBJECTIVE: We investigated sequence variations of the 29-kb insulin-like growth factor 2 (IGF2) region in human chromosome region 11p15.5 in the Korean population. This region consists of IGF2, insulin-like growth factor 2 antisense (IGF2AS), and the insulin gene, all important candidate genes for various diseases, including cancer, obesity, diabetes, and coronary disease. While single nucleotide polymorphisms...
Topics
- Adult
- Asian People
- Base Sequence
- Chromosomes, Human, Pair 11
- DNA Primers
- Female
- Gene Frequency
- Growth Substances
- Haplotypes
- Humans
- Insulin-Like Growth Factor II
