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Article

Sleeping Beauty transposon mutagenesis of the rat genome in spermatogonial stem cells.

Methods (San Diego, Calif.) - 1 Apr 2011

Ivics Zoltán, Izsvák Zsuzsanna, Chapman Karen M, Hamra F Kent

Abstract excerpt

Since several aspects of physiology in rats have evolved to be more similar to humans than that of mice, it is highly desirable to link the rat into the process of annotating the human genome with function. However, the lack of technology for generating defined mutants in the rat genome has hindered the identification of causative relationships between genes and disease phenotypes. As an important step towards...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21193047
DOI: 10.1016/j.ymeth.2010.12.014
PMCID: PMC3164264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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