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Article

Insertional mutagenesis by a hybrid piggyBac and sleeping beauty transposon in the rat.

Genetics - 1 Dec 2012

Furushima Kenryo, Jang Chuan-Wei, Chen Diane W, Xiao Ningna, Overbeek Paul A, Behringer Richard R

Abstract excerpt

A hybrid piggyBac/Sleeping Beauty transposon-based insertional mutagenesis system that can be mobilized by simple breeding was established in the rat. These transposons were engineered to include gene trap sequences and a tyrosinase (Tyr) pigmentation reporter to rescue the albinism of the geneti...

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Identifiers

PMID: 23023007
DOI: 10.1534/genetics.112.140855
PMCID: PMC3512136

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23023007-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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