Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic manipulations in the rat: progress and prospects.

Current opinion in nephrology and hypertension - 1 Jul 2011

Huang Guanyi, Ashton Charles, Kumbhani Dhruv S, Ying Qi-Long

Abstract excerpt

PURPOSE OF REVIEW: Several advances have been made to manipulate the rat genome in the last 2 years. This review aims to describe these advances in rat genetic manipulations, with an emphasis on their current status and their prospects and applications in the postgenomic era. RECENT FINDINGS: Authentic rat embryonic stem cells were derived in 2008 using the 2i/3i culture system. This led to the generation of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Models, Animal
Share to Gene Targeting
Share to Genetic Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Mutation

Share to Phenotype

Share to Rats, Transgenic

Source

Open in PubMed Open full text

Identifiers

PMID: 21546835
DOI: 10.1097/MNH.0b013e328347768a
PMCID: PMC3857098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic manipulations in the rat: progress and prospects.PMID 21546835Read ↗

Zinc-finger nucleases: new strategies to target the rat genome.Semantic proximity Read ↗

Generation of site-specific mutations in the rat genome via CRISPR/Cas9.Semantic proximity Read ↗

Sleeping Beauty transposon mutagenesis of the rat genome in spermatogonial stem cells.Semantic proximity Read ↗

Rat traps: filling the toolbox for manipulating the rat genome.Semantic proximity Read ↗

Genetic modification and screening in rat using haploid embryonic stem cells.Semantic proximity Read ↗

ENU mutagenesis to generate genetically modified rat models.Semantic proximity Read ↗

Rat models of human diseases and related phenotypes: a systematic inventory of the causative genesSemantic proximity Read ↗

Rat models of human diseases and related phenotypes: a systematic inventory of the causative genesSemantic proximity Read ↗

CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos.Semantic proximity Read ↗

Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation.Semantic proximity Read ↗

i-GONAD (improved genome-editing via oviductal nucleic acids delivery), a convenient in vivo tool to produce genome-edited rats.Semantic proximity Read ↗

Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.