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Article

Rat traps: filling the toolbox for manipulating the rat genome.

Genome biology - 1 Jan 2010

van Boxtel Ruben, Cuppen Edwin

Abstract excerpt

The laboratory rat is rapidly gaining momentum as a mammalian genetic model organism. Although traditional forward genetic approaches are well established, recent technological developments have enabled efficient gene targeting and mutant generation. Here we outline the current status, possibilities and application of these techniques in the rat.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20887642
DOI: 10.1186/gb-2010-11-9-217
PMCID: PMC2965381

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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