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Positional cloning of rat mutant genes reveals new functions of these genes.

Experimental animals - 21 Feb 2023

Kuramoto Takashi

Abstract excerpt

The laboratory rat (Rattus norvegicus) is a key model organism for biomedical research. Rats can be subjected to strict genetic and environmental controls. The rat's large body size is suitable for both surgical operations and repeated measurements of physiological parameters. These advantages have led to the development of numerous rat models for genetic diseases. Forward genetics is a proven approach for...

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PMID: 36058846
DOI: 10.1538/expanim.22-0089
PMCID: PMC9978133

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